Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins.

ABSTRACT:

Objectives

Astaxanthin is a dark red keto-carotenoid found in aquatic animals such as salmon and shrimp, and algae (Haematococcus pluvialis). Astaxanthin has a unique molecular structure that may facilitate anti-oxidative, immunomodulatory, and anti-inflammatory effects during physiological stress. The primary objective of this study was to examine the efficacy of 4-week ingestion of astaxanthin in moderating exercise-induced inflammation and immune dysfunction using a multi-omics approach.

Methods

This study employed a randomized, double blind, placebo controlled, crossover design with two 4-week supplementation periods and a 2-week washout period. Study participants were randomized to astaxanthin and placebo trials, with supplements ingested daily for 4 weeks prior to runn

SUBMITTER: Nieman DC 

PROVIDER: S-EPMC10070989 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature