Response Monitoring in Metastatic Breast Cancer: A Prospective Study Comparing ¹⁸F-FDG PET/CT with Conventional CT.

ABSTRACT: This study aimed to compare contrast-enhanced CT (CE-CT) and ¹⁸F-FDG PET/CT for response monitoring in metastatic breast cancer using the standardized response evaluation criteria RECIST 1.1 and PERCIST. The objective was to examine whether progressive disease was detected systematically earlier by one of the modalities. Methods: Women with biopsy-verified metastatic breast cancer were enrolled prospectively and monitored using combined CE-CT and ¹⁸F-FDG PET/CT every 9-12 wk to evaluate response to first-line treatment. CE-CT scans and RECIST 1.1 were used for clinical decision-making without accessing the ¹⁸F-FDG PET/CT scans. At study completion, ¹⁸F-FDG PET/CT scans were unmasked and assessed according to PERCIST. Visual assessment was

SUBMITTER: Vogsen M 

PROVIDER: S-EPMC10071809 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature