A review of research on the intersection between breast cancer and cardiovascular research in the Women's Health Initiative (WHI).

ABSTRACT: Both obesity and metabolic syndrome are linked to increased incidence of type 2 diabetes, cardiovascular disease (CVD), and cancers of the breast (post-menopausal), and other obesity-related cancers. Over the past 50 years, the worldwide prevalence of obesity and metabolic syndrome has increased, with a concomitant higher incidence of associated co-morbidities and mortality. The precise mechanism linking metabolic syndrome to increased cancer incidence is incompletely understood, however, individual components of metabolic syndrome have been linked to increased breast cancer incidence and worse survival. There is a bidirectional relationship between the risk of CVD and cancer due to a high burden of shared risk factors and higher rates of CVD among cancer survivors, which may be impacted b

SUBMITTER: Raychaudhuri S 

PROVIDER: S-EPMC10071996 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature