Maternal exposure to phthalates and total gestational weight gain in the LIFECODES birth cohort.

ABSTRACT: Excessive gestational weight gain contributes to adverse maternal and neonatal outcomes. Environmental exposures such as phthalates may lead to metabolic dysregulation, and studies suggest possible associations between maternal phthalate exposure and altered gestational weight gain. We assessed the association between nine maternal phthalate metabolites and measures of total gestational weight gain (pre-pregnancy to median 35.1 weeks of gestation) in a case-control study nested within LIFECODES (N = 379), a prospective birth cohort from Boston, Massachusetts (2006-2008). Our primary outcome was total gestational weight gain z score, a measure independent of gestational age that can provide a less biased estimate of this association. Our secondary outcomes were total gestational weight gain

SUBMITTER: Boyer TM 

PROVIDER: S-EPMC10073336 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature