Serum afamin levels in predicting gestational diabetes mellitus and preeclampsia: A systematic review and meta-analysis.

ABSTRACT:

Objectives

The association between biomarkers and the risk of gestational diabetes mellitus (GDM) or preeclampsia (PE) has been extensively studied. However, there is still a lack of convenient, specific, and sensitive indicators for early identification of GMD and PE. Therefore, we conducted a meta-analysis of published articles to investigate the value of afamin circulating levels in the early diagnosis of GDM and PE.

Methods

We searched the PubMed, Embase, Cochrane Library, and Web of Science databases for English studies published before November 16, 2022, that examined the association between afamin and GDM or PE. In addition, we searched Clinicaltrials.gov for the relevant completed and ongoing clinical trials. Pooled standard mean differences (SMDs) and weighted mean

SUBMITTER: Yuan Y 

PROVIDER: S-EPMC10073667 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature