Exploring the longitudinal associations of functional network connectivity and psychiatric symptom changes in youth.

ABSTRACT:

Background

Functional connectivity has been associated with psychiatric problems, both in children and adults, but inconsistencies are present across studies. Prior research has mostly focused on small clinical samples with cross-sectional designs.

Methods

We adopted a longitudinal design with repeated assessments to investigate associations between functional network connectivity (FNC) and psychiatric problems in youth (9- to 17-year-olds, two time points) from the general population. The largest single-site study of pediatric neurodevelopment was used: Generation R (N = 3,131 with data at either time point). Psychiatric symptoms were measured with the Child Behavioral Checklist as broadband internalizing and externalizing problems, and its eight specific syndrome scales (e

SUBMITTER: Dall'Aglio L 

PROVIDER: S-EPMC10074199 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature