Prevalence of Antiphospholipid Antibodies and Association With Incident Cardiovascular Events.

ABSTRACT:

Importance

The prevalence of antiphospholipid antibodies (aPL) and their association with future atherosclerotic cardiovascular disease (ASCVD) risk has yet to be thoroughly investigated.

Objective

To determine the association between measurements of aPL at a single time point and ASCVD risk in a diverse population.

Design, setting, and participants

This cohort study measured 8 aPL (anticardiolipin [aCL] IgG/IgM/IgA, anti-beta-2 glycoprotein I [aβ2GPI] IgG/IgM/IgA, and antiphosphatidylserine/prothrombin [aPS/PT] IgG/IgM) by solid-phase assays in plasma from participants of the Dallas Heart Study (DHS) phase 2, a multiethnic, population-based cohort study. Blood samples were collected between 2007 and 2009. The median follow-up was 8 years. Statistical analysis was per

SUBMITTER: Zuo Y 

PROVIDER: S-EPMC10074226 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature