Effects of SARS-CoV-2 vaccination on the severity of COVID-19 infection in patients on chronic dialysis.

ABSTRACT:

Background

COVID-19 is associated with increased morbidity and mortality in patients with end-stage kidney disease on dialysis. Efficacy of SARS-CoV-2 vaccination to prevent severe COVID-19 disease in end-stage kidney disease patients remains limited. We compared the incidence of COVID-19-related hospitalization and death in dialysis patients based on SARS-CoV-2 vaccine status.

Methods

Retrospective study of adults on chronic dialysis within Mayo Clinic Dialysis System in the Midwest (USA) between April 1st, 2020 and October 31st, 2022, who had a laboratory test positive for SARS-CoV-2 by PCR. Incidence of both COVID-19-related hospitalization and death were compared between vaccinated and unvaccinated patients.

Results

SARS-CoV-2 infection was identified in 309 patie

SUBMITTER: Miao J 

PROVIDER: S-EPMC10074356 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature