C-H bond activation via concerted metalation-deprotonation at a palladium(iii) center.

ABSTRACT: Herein we report the direct observation of C-H bond activation at an isolated mononuclear Pd(iii) center. The oxidation of the Pd(ii) complex (^MeN4)Pd^II(neophyl)Cl (neophyl = -CH₂C(CH₃)₂Ph; ^MeN4 = N,N'-dimethyl-2,11-diaza[3.3](2,6)pyridinophane) using the mild oxidant ferrocenium hexafluorophosphate (FcPF₆) yields the stable Pd(iii) complex [(^MeN4)Pd^III(neophyl)Cl]PF₆. Upon the addition of an acetate source, [(^MeN4)Pd^III(neophyl)Cl]PF₆ undergoes Csp²-H bond activation to yield the cyclometalated product [(^MeN4)Pd^III(cycloneophyl)]PF₆. This metalacycle can be independently prepared, allowing f

SUBMITTER: Bouley BS 

PROVIDER: S-EPMC10074423 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature