Metataxonomic analysis and host proteome response in dairy cows with high and low somatic cell count: a quarter level investigation.

ABSTRACT: Host response to invasive microbes in the bovine udder has an important role on the animal health and is essential to the dairy industry to ensure production of high-quality milk and reduce the mastitis incidence. To better understand the biology behind these host-microbiome interactions, we investigated the somatic cell proteomes at quarter level for four cows (collected before and after milking) using a shotgun proteomics approach. Simultaneously, we identified the quarter microbiota by amplicon sequencing to detect presence of mastitis pathogens or other commensal taxa. In total, 32 quarter milk samples were analyzed divided in two groups depending on the somatic cell count (SCC). The high SCC group (>100,000 cell/mL) included 10 samples and significant different proteome profiles were

SUBMITTER: Winther AR 

PROVIDER: S-EPMC10074679 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature