Attenuated facial movement in depressed women is associated with symptom severity, and nucleus accumbens functional connectivity.

ABSTRACT: It is assumed that mood can be inferred from one's facial expression. While this association may prove to be an objective marker for mood disorders, few studies have explicitly evaluated this linkage. The facial movement responses of women with major depressive disorder (n = 66) and healthy controls (n = 46) under emotional stimuli were recorded using webcam. To boost facial movements, the naturalistic audio-visual stimuli were presented. To assess consistent global patterns across facial movements, scores for facial action units were extracted and projected onto principal component using principal component analysis. The associations of component for facial movements with functional brain circuitry was also investigated. Clusters of mouth movements, such as lip press and stretch, identifi

SUBMITTER: Jung C 

PROVIDER: S-EPMC10074984 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature