Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC10074990 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Liu Yiwen Y Zhou Fuyou F Yang Haijun H Zhang Zheyuan Z Zhang Jiahao J He Keyao K Qian Mengfan M Li Ruonan R Sun Wei W Dai Ningtao N Li Junkuo J Guo Yibo Y Kong Jinyu J Gao Shegan S
Translational oncology 20230327
Our prior studies have confirmed that long-term colonization of Porphyromonas gingivalis (Pg) and overexpression of the inflammatory factor glycogen synthase kinase 3β (GSK3β) promote the malignant evolution of esophageal squamous cell carcinoma (ESCC). We aimed to investigate the functional mechanism by which Pg could promote ESCC malignancy and chemo-resistance through GSK3β-mediated mitochondrial oxidative phosphorylation (mtOXPHOS), and the clinical implications. The effects of Pg and GSK3β ...[more]