The default mode network is affected in the early stage of simian immunodeficiency virus infection: a longitudinal study.

ABSTRACT: Acquired immune deficiency syndrome infection can lead to cognitive dysfunction represented by changes in the default mode network. Most recent studies have been cross-sectional and thus have not revealed dynamic changes in the default mode network following acquired immune deficiency syndrome infection and antiretroviral therapy. Specifically, when brain imaging data at only one time point are analyzed, determining the duration at which the default mode network is the most effective following antiretroviral therapy after the occurrence of acquired immune deficiency syndrome. However, because infection times and other factors are often uncertain, longitudinal studies cannot be conducted directly in the clinic. Therefore, in this study, we performed a longitudinal study on the dynamic chang

SUBMITTER: Tang ZC 

PROVIDER: S-EPMC10075116 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature