Neurogenic marker expression in differentiating human adipose derived adult mesenchymal stem cells.

ABSTRACT:

Background

Adipose-derived stem cells (ADSCs) are increasingly utilised in the field of neural regeneration due to their high accessibility and capacity for differentiation into neural like cells. Culturing ADSCs in the presence of various growth factors, small molecules and combinations thereof have shown promise in this regard; however, these protocols are generally complex, time-consuming and costly. The need for commercially available and chemically defined growth media/supplements is required to facilitate further developments in this area.

Methods

In this study, we have examined the neural differentiation and proliferation potential of the commercially available supplements B27, CultureOne (C1) and N2 on human ADSCs (hADSCs). Through a combination of immunocytochemistr

SUBMITTER: Pelegri NG 

PROVIDER: S-EPMC10076228 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature