Relationship between change in social evaluation learning and mood in early antidepressant treatment: A prospective cohort study in primary care.

ABSTRACT:

Background

Antidepressants are proposed to work by increasing sensitivity to positive versus negative information. Increasing positive affective learning within social contexts may help remediate negative self-schema. We investigated the association between change in biased learning of social evaluations about the self and others, and mood during early antidepressant treatment.

Method

Prospective cohort assessing patients recruited from primary care in South West England at four timepoints over the first 8 weeks of antidepressant treatment (n = 29). At each timepoint, participants completed self-report measures of depression (Beck Depression Inventory II (BDI-II) and Patient Health Questionnaire 9 (PHQ-9)), anxiety (Generalised Anxiety Disorder Questionnaire 7 (GAD-7)

SUBMITTER: Hobbs C 

PROVIDER: S-EPMC10076340 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature