Cortical thinning in male obstructive sleep apnoea patients with excessive daytime sleepiness.

ABSTRACT:

Background and purpose

Obstructive sleep apnoea is associated with excessive daytime sleepiness due to sleep fragmentation and hypoxemia, both of which can lead to abnormal brain morphology. However, the pattern of brain structural changes associated with excessive daytime sleepiness is still unclear. This study aims to investigate the effects of excessive daytime sleepiness on cortical thickness in patients with obstructive sleep apnoea.

Materials and methods

61 male patients with newly diagnosed obstructive sleep apnoea were included in the present study. Polysomnography and structural MRI were performed for each participant. Subjective daytime sleepiness was assessed using the Epworth Sleepiness Scale score. Surface-based morphometric analysis was performed using Statisti

SUBMITTER: Li Y 

PROVIDER: S-EPMC10076663 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature