Deep brain stimulation in posterior subthalamic area for Holmes tremor: Case reports with review of the literature.

ABSTRACT:

Background

Holmes tremor (HT) is a refractory tremor associated with cortico-basal ganglia loops and cerebellothalamic tract abnormalities. Various drug treatments have been attempted; however, no treatment method has yet been established. Historically, thalamic deep brain stimulation (DBS) has been performed in medically refractory cases. Recently, the posterior subthalamic area (PSA) has been used for HT. Here, we report cases of HT and review the effectiveness and safety of PSA-DBS for HT.

Cases

We conducted a retrospective chart review of two patients with HT who underwent PSA-DBS. Improvement in tremors was observed 1 year after surgery without apparent complications.

Literature review

We identified 12 patients who underwent PSA-DBS for HT, including our cases. I

SUBMITTER: Kamo H 

PROVIDER: S-EPMC10076748 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature