Glucocorticoids and physical performance: A systematic review with meta-analysis of randomized controlled trials.

ABSTRACT:

Introduction

This systematic review with meta-analysis investigates the effect of glucocorticoids on maximal and submaximal performance in healthy subjects.

Methods

We searched for randomised controlled trials investigating the effect of glucocorticoids on physical performance in Web of Science, Scopus, Medline, Embase and SportDiscus in March 2021. Risk of bias was assessed with the revised Cochrane Collaboration Risk of Bias Tool (RoB2). Data from random effect models are presented as standardized difference in mean (SDM) with 95% confidence interval. We included 15 studies comprising 175 subjects.

Results

Two studies had high risk of bias. Glucocorticoids had a small positive effect on maximal physical performance compared to placebo (SDM 0.300, 95% CI 0.080 to 0.5

SUBMITTER: Riiser A 

PROVIDER: S-EPMC10076788 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature