Predictors of postoperative biochemical remission in acromegaly.

ABSTRACT:

Purpose

Acromegaly is a rare neuroendocrine condition that can lead to significant morbidity. Despite China's vast population size, studies on acromegaly remain sparse. This study aimed to investigate the clinical characteristics and predictors of biochemical remission after surgery for acromegaly using the China Acromegaly Patient Association (CAPA) database.

Methods

A retrospective nationwide study was conducted using patient-reported data from CAPA database between 1998 and 2018. The principal component analysis (PCA) and logistic regression analysis were employed to determine independent predictors of biochemical remission at 3 months in patients after surgery.

Results

Of the 546 surgical cases (mean age: 36.8 years; 59.5% females), macroadenomas and invasive tumo

SUBMITTER: Yao S 

PROVIDER: S-EPMC10077515 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature