The incomplete circle of Willis is associated with vulnerable intracranial plaque features and acute ischemic stroke.

ABSTRACT:

Background

The circle of Willis (CoW) plays a significant role in intracranial atherosclerosis (ICAS). This study investigated the relationship between different types of CoW, atherosclerosis plaque features, and acute ischemic stroke (AIS).

Methods

We investigated 97 participants with AIS or transient ischemic attacks (TIA) underwent pre- and post-contrast 3T vessel wall cardiovascular magnetic resonance within 7 days of the onset of symptoms. The culprit plaque characteristics (including enhancement grade, enhancement ratio, high signal in T₁, irregularity of plaque surface, and normalized wall index), and vessel remodeling (including arterial remodeling ratio and positive remodeling) for lesions were evaluated. The anatomic structures of the anterior and the po

SUBMITTER: Wang H 

PROVIDER: S-EPMC10077703 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature