Platelets and platelet-derived vesicles as an innovative cellular and subcellular platform for managing multiple sclerosis.

ABSTRACT:

Introduction

Multiple sclerosis (MS) is a progressive inflammatory autoimmune disease that involves young individuals. The drug delivery systems now are available for this disease have chronic and non-targeted effects on the patients. Because of the presence of BBB (blood-brain-barrier), their concentration in the CNS (central nervous system) is low. Because of this flaw, it is critical to use innovative active targeted drug delivery methods.

Result

Platelets are blood cells that circulate freely and play an important role in blood hemostasis. In this review, we emphasize the various roles of activated platelets in the inflammatory condition to recruit other cells to the injured area and limit inflammation. Besides, the activated platelets in the different stages of the MS d

SUBMITTER: Mehdi-Alamdarlou S 

PROVIDER: S-EPMC10078055 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature