New methods for robust continuous wave T_1ρ relaxation preparation.

ABSTRACT: Measurement of the longitudinal relaxation time in the rotating frame of reference (T_1ρ ) is sensitive to the fidelity of the main imaging magnetic field (B₀ ) and that of the RF pulse (B₁ ). The purpose of this study was to introduce methods for producing continuous wave (CW) T_1ρ contrast with improved robustness against field inhomogeneities and to compare the sensitivities of several existing and the novel T_1ρ contrast generation methods with the B₀ and B₁ field inhomogeneities. Four hard-pulse and four adiabatic CW-T_1ρ magnetization preparations were investigated. Bloch simulations and experimental measurements at different spin-lock amplitudes under ideal and non-ideal conditions, as well as theore

SUBMITTER: Pala S 

PROVIDER: S-EPMC10078184 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature