The impact of preservation fluid culture on graft site arteritis: A systematic review and meta-analysis.

ABSTRACT:

Background

The role of culturing the graft preservation fluid (PF) is controversial and its impact on graft arteritis development remains unclear.

Methods

Systematic literature search retrieving observational studies comparing solid organ transplant (SOT) recipients with culture-positive PF versus culture-negative PF. The quality of included studies was independently assessed according to the ROBINS-I tool for observational studies. Meta-analysis was performed using Mantel-Haenszel random-effect models. Graft site arteritis within 180 days from transplant was selected as the primary outcome.

Results

Twenty-one observational studies (N = 2208 positive PF vs. 4458 negative) were included. Among positive PF, 857 (38.8%) were classified as high-risk group pathogens and 13

SUBMITTER: Rinaldi M 

PROVIDER: S-EPMC10078333 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature