Effects of carnosine on the embryonic development and TiO₂ nanoparticles-induced oxidative stress on Zebrafish.

ABSTRACT: Oxidative stress is due to an unbalance between pro-oxidants, such as reactive oxygen (ROS) and nitrogen (RNS) species, and antioxidants/antioxidant system. Under physiological conditions these species are involved in different cellular processes such as cellular homeostasis and immune response, while an excessive production of ROS/RNS has been linked to the development of various diseases such as cancer, diabetes, and Alzheimer's disease. In this context, the naturally occurring dipeptide carnosine has shown the ability to scavenge ROS, counteract lipid peroxidation, and inhibit proteins oxidation. Titanium dioxide nanoparticles (TiO₂-NPs) have been widely used to produce cosmetics, in wastewater treatment, in food industry, and in healthcare product. As consequence, these NPs

SUBMITTER: Caruso G 

PROVIDER: S-EPMC10078361 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature