Neuroinvasive West Nile virus infections after solid organ transplantation: Single center experience and systematic review.

ABSTRACT: West Nile virus (WNv) is a major cause of viral encephalitis in the United States. WNv infection is usually asymptomatic or a limited febrile illness in the immunocompetent hosts, although a small percentage can develop neuroinvasive disease. Neuroinvasive disease due to WNv in solid organ transplant recipients occurs at higher rates than observed in the general population and can have long term neurological sequalae.

Methods

We retrospectively reviewed medical records of all solid organ transplant recipients at our institution who tested positive for WNv from 2010 to 2018. Two reviewers performed electronic searches of Medline, Embase, Cochrane Library of literature of WNv infections in SOT. Descriptive statistics were performed on key variables.

Results

Eight recipients (me

SUBMITTER: Abbas A 

PROVIDER: S-EPMC10078393 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature