Systematic review: Clinical effectiveness of interventions for the treatment of nocturnal gastroesophageal reflux.

ABSTRACT:

Background

Nocturnal gastroesophageal reflux symptoms have a major impact on sleep quality and are associated with complicated gastroesophageal reflux disease (GERD). We performed a systematic review to assess the data on the effectiveness of the currently available interventions for the treatment of nocturnal reflux symptoms.

Methods

We searched PubMed, EMBASE, and the Cochrane Library. All prospective, controlled, and uncontrolled clinical trials in adult patients describing interventions (lifestyle modifications, surgical and pharmacological) for nocturnal gastroesophageal reflux symptoms were assessed for eligibility. A narrative descriptive summary of findings is presented together with summary tables for study characteristics and quality assessment.

Key results

SUBMITTER: Schuitenmaker JM 

PROVIDER: S-EPMC10078437 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature