Diagnostic characteristics of refractometry cut-off points for the estimation of immunoglobulin G concentration in mare colostrum.

ABSTRACT:

Background

Feeding foals with poor quality colostrum predisposes them to failure of passive transfer (FPT). FPT is a major risk factor for neonatal infections.

Objectives

To assess the optimal cut-offs for the optical (OR) and digital (DR) refractometer and determine their accuracy for poor quality colostrum diagnosis.

Study design

A diagnostic validation study.

Methods

Eighty-one colostrum samples and sera were collected from broodmares and their neonatal foals, respectively. Colostral and serum IgG concentrations were measured by radial immunodiffusion (RID), DR and OR. Correlation coefficients were calculated. ROC curves were generated to identify optimal cut-offs for the refractometers and their diagnostic characteristics were evaluated.

Results

The

SUBMITTER: Rampacci E 

PROVIDER: S-EPMC10078710 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature