The impact of COVID-19 in children with Sickle Cell Disease: Results of a multicentric registry.

ABSTRACT:

Objective

To analyze the outcomes of children with sickle cell disease (SCD) and COVID-19.

Method

A multicenter prospective study was conducted in five hematological centers from Central and Southeast Brazil, starting in April 2020. The variables recorded include clinical symptoms, diagnostic methods, therapeutic measures, and treatment sites. The clinical repercussions of the infection on the initial treatment and the overall prognosis were also evaluated.

Results

Twenty-five unvaccinated children, aged 4 to 17 years, with SCD and a positive SARS-CoV-2 RT-PCR result participated in this study. Patients were classified as SCD types SS (n = 20, 80%) and SC (n = 5, 20%). Clinical characteristics and evolution were similar in both groups (p>0.05), except for the fetal he

SUBMITTER: Oliveira CM 

PROVIDER: S-EPMC10079108 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature