The impact of long-term conditions on the progression of frailty.

ABSTRACT:

Objective

To explore longitudinally the impact of multiple long-term conditions (LTCs) on frailty progression separately for males and females.

Methods

A functional frailty measure (FFM) was used to examine putative determinants of frailty progression among participants aged 65 to 90 in the English Longitudinal Study of Ageing (ELSA), across nine waves (18 years) of data collection. A multilevel growth model was fitted to measure the FFM progression over 18 years, grouped by LTC categories (zero, one, two and more).

Results

There were 2396 male participants at wave 1, of whom 742 (31.0%) had 1 LTC and 1147 (47.9%) had ≥2 LTCs. There were 2965 females at wave 1 of whom 881 (29.7%) had one LTC and 1584 (53.4%) had ≥2 LTCs. The FFM increased 4% each 10 years for the male

SUBMITTER: Alattas A 

PROVIDER: S-EPMC10079116 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature