CelltrackR: An R package for fast and flexible analysis of immune cell migration data.

ABSTRACT: Visualization of cell migration via time-lapse microscopy has greatly advanced our understanding of the immune system. However, subtle differences in migration dynamics are easily obscured by biases and imaging artifacts. While several analysis methods have been suggested to address these issues, an integrated tool implementing them is currently lacking. Here, we present celltrackR, an R package containing a diverse set of state-of-the-art analysis methods for (immune) cell tracks. CelltrackR supports the complete pipeline for track analysis by providing methods for data management, quality control, extracting and visualizing migration statistics, clustering tracks, and simulating cell migration. CelltrackR supports the analysis of both 2D and 3D cell tracks. CelltrackR is an open-source p

SUBMITTER: Wortel IMN 

PROVIDER: S-EPMC10079262 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature