Neighborhood disadvantage is associated with decreased ovarian reserve in women with overweight and obesity.

ABSTRACT:

Objective(s)

To evaluate the association between neighborhood disadvantage and ovarian reserve stratified by body mass index (BMI).

Design

Cross-sectional cohort study.

Setting

Single academic medical center.

Patient(s)

A total of 193 healthy reproductive-age women with regular menstrual cycles in the St. Louis, Missouri metropolitan area.

Intervention(s)

Residence in a disadvantaged neighborhood.

Main outcome measure(s)

Ovarian reserve as assessed by ovarian antral follicle count (AFC) and serum anti-Müllerian hormone (AMH) concentration.

Result(s)

Women (n = 193) ranged from 20 to 44 years. The majority had overweight or obesity (59%, n = 117) with mean BMI of 28±7 kg/m². Forty-eight women lived in the most disadvantaged neighb

SUBMITTER: Komorowski AS 

PROVIDER: S-EPMC10079614 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature