Surfactant Micellar and Vesicle Microenvironments and Structures under Synthetic Organic Conditions.

ABSTRACT: Fluorescence lifetime imaging microscopy (FLIM) reveals vesicle sizes, structures, microenvironments, reagent partitioning, and system evolution with two chemical reactions for widely used surfactant-water systems under conditions relevant to organic synthesis, including during steps of Negishi cross-coupling reactions. In contrast to previous investigations, the present experiments characterize surfactant systems with representative organohalide substrates at high concentrations (0.5 M) that are reflective of the preparative-scale organic reactions performed and reported in water. In the presence of representative organic substrates, 2-iodoethylbenzene and 2-bromo-6-methoxypyridine, micelles swell into emulsion droplets that are up to 20 μm in diameter, which is 3-4 orders of magnitude la

SUBMITTER: Peacock H 

PROVIDER: S-EPMC10079647 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature