Multiple-site decontamination to prevent acquired infection in patients with veno-venous ECMO support.

ABSTRACT:

Background

Acute distress respiratory syndrome (ARDS) patients with veno-venous extra corporeal membrane oxygenation (ECMO) support are particularly exposed to ECMO-associated infection (ECMO-AI). Unfortunately, data regarding AI prophylaxis in this setting are lacking. Selective decontamination regimens decrease AI incidence, including ventilator-associated pneumonia (VAP) and bloodstream infection (BSI) in critically ill patients. We hypothesized that a multiple-site decontamination (MSD) regimen is associated with a reduction in the incidence of AI among VV-ECMO patients.

Methods

We conducted a retrospective observational study in three French ECMO referral centers from January 2010 to December 2021. All adult patients (> 18 years old) who received VV-ECMO support for ARD

SUBMITTER: Massart N 

PROVIDER: S-EPMC10079793 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature