Relation between ocular paraneoplastic syndromes and Immune Checkpoint Inhibitors (ICI): review of literature.

ABSTRACT:

Purpose

To describe different ocular paraneoplastic syndromes in patients treated with Immune Checkpoint Inhibitors (ICI), its relation with different types of ICI and different types of tumors, and its implications for treatment.

Methods

A comprehensive review of the literature was performed.

Results

Patients treated with ICI can present with different ocular paraneoplastic syndromes, such as Carcinoma Associated Retinopathy (CAR), Melanoma Associated Retinopathy (MAR) and paraneoplastic Acute Exudative Polymorphous Vitelliform Maculopathy (pAEPVM). In literature, the different types of paraneoplastic retinopathy are mostly related to different types of primary tumors, with MAR and pAEPVM seen in melanoma, and CAR in carcinoma. Visual prognosis is limited in MAR and

SUBMITTER: Casselman P 

PROVIDER: S-EPMC10079794 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature