Comprehensive analysis of the expression, prognostic value and biological importance of OVO‑like proteins in clear cell renal cell carcinoma.

ABSTRACT: This study examined the expression levels of OVO-like proteins (OVOLs) in clear cell renal cell carcinoma (ccRCC) tissues and their value in predicting disease prognosis. The transcript levels, genetic alterations, and biological functions of OVOLs and their correlation with tumor immune cell infiltration and drug sensitivity and survival outcomes, as well as their prognostic values, in patients with ccRCC were analyzed based on data obtained from The Cancer Genome Atlas, Gene Expression Profiling Interactive Analysis, cBioPortal, and GSCALite databases. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were performed using R software (Bioconductor, clusterProfiler packages). A protein-protein interaction network was established and visualized using the R software with the

SUBMITTER: Lin J 

PROVIDER: S-EPMC10079820 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature