Inference of transcriptome signatures of Escherichia coli in long-term stationary phase.

ABSTRACT: "Non-growing" is a dominant life form of microorganisms in nature, where available nutrients and resources are limited. In laboratory culture systems, Escherichia coli can survive for years under starvation, denoted as long-term stationary phase, where a small fraction of cells manages to survive by recycling resources released from nonviable cells. Although the physiology by which viable cells in long-term stationary phase adapt to prolonged starvation is of great interest, their genome-wide response has not been fully understood. In this study, we analyzed transcriptional profiles of cells exposed to the supernatant of 30-day long-term stationary phase culture and found that their transcriptome profiles displayed several similar responses to those of cells in the 16-h short-term stationa

SUBMITTER: Takano S 

PROVIDER: S-EPMC10079935 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature