Dynamic peripheral nerve stimulation can produce cortical activation similar to punctate mechanical stimuli.

ABSTRACT: During contact, phasic and tonic responses provide feedback that is used for task performance and perceptual processes. These disparate temporal dynamics are carried in peripheral nerves, and produce overlapping signals in cortex. Using longitudinal intrafascicular electrodes inserted into the median nerve of a nonhuman primate, we delivered composite stimulation consisting of onset and release bursts to capture rapidly adapting responses and sustained stochastic stimulation to capture the ongoing response of slowly adapting receptors. To measure the stimulation's effectiveness in producing natural responses, we monitored the local field potential in somatosensory cortex. We compared the cortical responses to peripheral nerve stimulation and vibrotactile/punctate stimulation of the fingert

SUBMITTER: Tanner J 

PROVIDER: S-EPMC10079952 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature