Targeted therapy and immunotherapy: Diamonds in the rough in the treatment of epithelial ovarian cancer.

ABSTRACT: Currently, for ovarian cancer, which has the highest mortality rate among all gynecological cancers, the standard treatment protocol is initial tumor cytoreductive surgery followed by platinum-based combination chemotherapy. Although the survival rate after standard treatment has improved, the therapeutic effect of traditional chemotherapy is very limited due to problems such as resistance to platinum-based drugs and recurrence. With the advent of the precision medicine era, molecular targeted therapy has gradually entered clinicians' view, and individualized precision therapy has been realized, surpassing the limitations of traditional therapy. The detection of genetic mutations affecting treatment, especially breast cancer susceptibility gene (BRCA) mutations and mutations of other homol

SUBMITTER: Huang X 

PROVIDER: S-EPMC10080064 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature