B-cell non-Hodgkin lymphoma of the breast in Waldenstrom's macroglobulinemia: a case report.

ABSTRACT:

Background

Non-Hodgkin lymphoma (NHL) of the breast is a rare disease and can occur amongst patients affected by Waldenström's Macroglobulinemia (WM). WM is an indolent B-cell lymphoproliferative disorder with an overall incidence of about 1/100,000 in Europe. Breast imaging is not specific to breast lymphoma that often mimics benign lesions. The diagnosis is based on breast biopsy, the presence of MYD88L265P somatic mutation and immunoglobulin M (IgM) paraprotein detectable in the setting of lymphoplasmacytic infiltration by bone marrow (BM) biopsy.

Case description

A 60-year-old woman with personal and familial history of monoclonal gammopathy of undetermined significance (MGUS) and a lump in her right breast was referred to our hospital. Standard imaging showed round mass

SUBMITTER: Esposito E 

PROVIDER: S-EPMC10080316 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature