A case report of oral sulfamethoxazole in the treatment of posttransplant Listeria monocytogenes meningitis.

ABSTRACT:

Background

Renal transplant recipients are prone to Listeria monocytogenes (Lm) infection due to immunosuppressive therapies. Ampicillin or penicillin G is regarded as the first-line treatment of Lm meningitis. For patients with allergy to penicillin, convention to trimethoprim-sulfamethoxazole (TMP-SMX) iv should ideally be performed since TMP-SMX remarkable bactericidal activity. But there's still scarcity of reports indicating oral TMP-SMX regimen on Lm meningitis.

Case description

A 30-year-old male who received a renal transplant 4 months ago was admitted to the hospital with generalized pain and headache for 3 days accompanied by diarrhea and fever for 1 day. The patient had been treated with regular oral immunosuppressants post-transplantation. After admission,

SUBMITTER: Ma Y 

PROVIDER: S-EPMC10080344 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature