The utility of clinical registries for guiding clinical practice in upper tract urothelial cancer: a narrative review.

ABSTRACT:

Background and objective

Upper tract urothelial cancer (UTUC) lacks high-quality evidence to appraise current patterns of presentation, diagnosis, treatment and outcomes as a result of disease rarity and patient heterogeneity. Registries may overcome many of the challenges making clinical trials challenging in UTUC and provide answers to many of the clinical questions that afflict UTUC management. In this narrative review we aim to summarise the design of registries that have contributed to the UTUC literature, discuss their strengths and limitations and the future directions of registries in UTUC.

Methods

Two independent reviewers conducted a search of the OVID MEDLINE database from July 2002-July 2022. Included articles were required to be published in peer reviewed journa

SUBMITTER: Kealey J 

PROVIDER: S-EPMC10080345 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature