Elemental profiles in distant tissues during tumor progression.

ABSTRACT:

Background

Essential elements have functions in tumor progression by promoting protumoral cellular processes, such as proliferation, and migration, among others. Obtaining an understanding of how these elements relate to tumor progression processes is of great importance for research. Elemental profile studies in distant tissues, which can be modulated by tumor cells to promote metastasis, have not been sufficiently investigated. The main goal of this study is to evaluate multielemental distribution during tumor progression, focusing on tumor tissue and distant tissues that may be affected.

Methods

Tumor progression in vivo was simulated by inoculating C57BL/6 mice with Lewis Lung Carcinoma (LLC) cells. Samples of the primary tumor and distant tissues were collected during 5

SUBMITTER: Salles S 

PROVIDER: S-EPMC10080929 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature