Sex differences in hepatic ischemia‒reperfusion injury: a cross-sectional study.

ABSTRACT: Several studies have shown that males suffer more severe damage than females in the process of ischemia and reperfusion of the brain, heart and kidney. Accordingly, our study will reveal the correlation between the severity of hepatic ischemia‒reperfusion injury (HIRI) and sex, and preliminarily analyze the underlying mechanism. A total of 75 patients who were considered to have "benign liver tumors" at the initial admission and underwent partial hepatectomy were enrolled. We identified potential differences between different groups and discussed the correlation between the severity of HIRI and sex through a comparative analysis. Results showed that HIRI was more severe in males than in females, especially in younger patients. To explore whether estrogen level differences are the main reas

SUBMITTER: Li Z 

PROVIDER: S-EPMC10081297 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature