Event-related potential (ERP) evidence of early visual processing differences in cystinosis.

ABSTRACT: Cystinosis, a rare lysosomal storage disease, is characterized by cystine crystallization and accumulation within tissues and organs, including the kidneys and brain. Its impact on neural function appears mild relative to its effects on other organs, but therapeutic advances have led to substantially increased life expectancy, necessitating deeper understanding of its impact on neurocognitive function. Behavioral difficulties have been reported in cystinosis in the visual and visual-processing domain. Very little is known, however, about how the brains of people living with cystinosis process visual information, although cysteamine accumulation in the retina is a prominent feature of cystinosis. Here, electrophysiology was recorded during a Go/No-Go task to investigate early visual process

SUBMITTER: Horsthuis DJ 

PROVIDER: S-EPMC10081319 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature