Peripheral cortical bone density predicts vertebral bone mineral properties in spine fusion surgery patients.

ABSTRACT: Spine fusion surgery is one of the most common orthopedic procedures, with over 400,000 performed annually to correct deformities and pain. However, complications occur in approximately one third of cases. While many of these complications may be related to poor bone quality, it is difficult to detect bone abnormalities prior to surgery. Areal BMD (aBMD) assessed by DXA may be artifactually high in patients with spine pathology, leading to missed diagnosis of deficits. In this study, we related preoperative imaging characteristics of both central and peripheral sites to direct measurements of bone quality in vertebral biopsies. We hypothesized that pre-operative imaging outcomes would relate to vertebral bone mineralization and collagen properties. Pre-operative assessments included DXA me

SUBMITTER: Heilbronner AK 

PROVIDER: S-EPMC10081687 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature