Multiple Organ Dysfunction and Critically Ill Children With Acute Myeloid Leukemia: Single-Center Retrospective Cohort Study.

ABSTRACT:

Objectives

To describe the prevalence of multiple organ dysfunction syndrome (MODS) and critical care utilization in children and young adults with acute myeloid leukemia (AML) who have not undergone hematopoietic cell transplantation (HCT).

Design

Retrospective cohort study of MODS (defined as dysfunction of two or more organ systems) occurring any day within the first 72 hours of PICU admission.

Setting

Large, quaternary-care children's hospital.

Patients

Patients 1 month through 26 years old who were treated for AML from 2011-2019.

Interventions

None.

Measurements and main results

Eighty patients with AML were included. These 80 patients had a total of 409 total non-HCT-related hospital and 71 PICU admissions. The majority 53 of 71 of PICU admi

SUBMITTER: Gaugler M 

PROVIDER: S-EPMC10081947 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature