The unraveling of balanced complexes in metabolic networks.

ABSTRACT: Balanced complexes in biochemical networks are at core of several theoretical and computational approaches that make statements about the properties of the steady states supported by the network. Recent computational approaches have employed balanced complexes to reduce metabolic networks, while ensuring preservation of particular steady-state properties; however, the underlying factors leading to the formation of balanced complexes have not been studied, yet. Here, we present a number of factorizations providing insights in mechanisms that lead to the origins of the corresponding balanced complexes. The proposed factorizations enable us to categorize balanced complexes into four distinct classes, each with specific origins and characteristics. They also provide the means to efficiently de

SUBMITTER: Langary D 

PROVIDER: S-EPMC10082078 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature