Dose escalation in oropharyngeal cancer: a comparison of simultaneous integrated boost and brachytherapy boost.

ABSTRACT:

Background

Local recurrence is the most common pattern of failure in head and neck cancer. It can therefore be hypothesised that some of these patients would benefit from an intensified local treatment, such as radiation dose escalation of the primary tumour. This study compares treatment and toxicity outcomes from two different boost modalities in oropharyngeal cancer: simultaneous integrated boost (SIB) and brachytherapy boost.

Methods

Two hundred and forty-four consecutive patients treated with > 72 Gy for oropharyngeal squamous cell carcinoma between 2011 and 2018 at our institution were retrospectively analysed. Data on side effects were collected from a local quality registry and supplemented with a review of medical records. Patients receiving a brachytherapy boost fi

SUBMITTER: Embring A 

PROVIDER: S-EPMC10082532 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature