Whole-genome sequencing of Histophilus somni strains isolated in Russia.

ABSTRACT:

Background and aim

Histophilus somni is a Gram-negative bacterium belonging to the Pasteurellaceae family that can cause bovine histophilosis. Histophilus may act as a commensal or opportunistic bacterial cattle pathogen. Comparing genomes of the pathogenic strain 2336 with the non-pathogenic preputial 129Pt isolate revealed some putative virulence factors. The study of the complete genomes of H. somni strains circulating in Russia has never been conducted before. This study aimed to identify genetic features of the H. somni strains isolated in Russia and evaluate the possibility of using strains for vaccine development.

Materials and methods

Three strains of H. somni were isolated from different sources. Strain 188-VIEV was isolated

SUBMITTER: Yatsentyuk S 

PROVIDER: S-EPMC10082713 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature