Prognostic value of pre-therapeutic FDG-PET radiomic analysis in gastro-esophageal junction cancer.

ABSTRACT: The main aim of this study was to evaluate the prognostic value of radiomic approach in pre-therapeutic ¹⁸F-fluorodeoxyglucose positron-emission tomography (FDG-PET/CT) in a large cohort of patients with gastro-esophageal junction cancer (GEJC). This was a retrospective monocenter study including 97 consecutive patients with GEJC who underwent a pre-therapeutic FDG-PET and were followed up for 3 years. Standard first-order radiomic PET indices including SUV_max, SUV_mean, SUV_peak, MTV and TLG and 32 textural features (TFs) were calculated using LIFEx software on PET imaging. Prognostic significance of these parameters was assessed in univariate and multivariate analysis. Relapse-free survival (RFS) and overall survival (OS) were respectively chosen

SUBMITTER: Amrane K 

PROVIDER: S-EPMC10082755 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature